OBJETIVO: Analisar o perfil clínico de portadores de câncer colorretal (CCR). MÉTODOS: Estudo prospectivo com 390 pacientes submetidos a colonoscopia. 152 assintomáticos Grupo A (G-A) e 238 sintomáticos com CCR Grupo B (G-B). Analisamos história familiar (HF), sintomas, Índice de massa Corpórea (IMC), localização do tumor e histopatologia. P<0,05 foi considerado significativo. RESULTADOS: Média de idade, 62+/-9 G-A e 61+/-13 G-B, P>0,05. HF positiva em 79 (31%) com CCR, contra 34 (32%) sem câncer, P>0,05. IMC no G-A foi 25+/-4 contra 27+/-4 no G-B P>0,05. No G-A 9 (5,9%) tiveram CCR. Câncer superficial em 1 (11%) no G-A contra 21 (8,8%) no G-B, P>0,05. Câncer em cólon esquerdo em 6 (66%) no G-A contra 168 (69%) no G-B, P>0,05. Alteração do hábito intestinal com sangue, cólon esquerdo 56 (60%) contra 13 (31%) no direito P<0,01. Emagrecimento com anemia mais freqüentes em tumor de cólon direito quando comparado com esquerdo, 30 (44%) versus 31 (17%) e 36 (46%) versus 15 (8%) p<0,01. Sintomas há mais de 6 meses em 157 (63%) Adenocarcinoma moderadamente diferenciado em 166 (67%), bem diferenciado em 63 (25%) e pouco diferenciado em 18 (7%). CONCLUSÕES: O perfil de risco para CCR precisa ser aprimorado.
PURPOSE: Analyze the profile of colon and rectal cancer. METHODS: 390 colonoscopies were performed in 152 asymptomatic people Group A and 238 colon cancer patients with diagnosis done at colonoscopy Group B. Age, family history (FH), symptoms, Body Mass Index (BMI), location of the tumor and histopathology were analyzed. P value<0,05 was significant. RESULTS: Mean age Group A 62+/-9 years and 61+/-13 Group B P>0,95. 79 patients (31%) of cancer had positive FH and positive FH was present in 34 patients without cancer (23%) P>0,05.BMI was 26+/-4 Group A and 27+/- for B P>0,05 9 patients (5,9%) from Group A was found to have cancer. Superficial in 1 (11%) Group A against 21 (8,8%) for Group B P>0,05. Change of bowel habits with bleeding was 56 (60%) on the left colon cancer against 13 (31%) on the right P<0,01. Weight loss and anemia occurred more frequently on the right when compared to the left 30 (44%) X 31 (17%) and 36 (46%) X 15 (8%) P<0,01. 157 patients (63%) had symptoms for more than 6 months. Moderated-differentiated adenocarcinoma was found in 166 (67%), well-differentiated 63 (25%) and poorly-differentiated in 18 (7%) of the patients. CONCLUSION: The profile of CRC must be better studied.